Palladium-catalyzed allylic C-H alkylation of terminal olefins with 3-carboxamide oxindoles.

• Tác giả: Guojuan Liang, Gaochen Liu, Xing Liu, Dexin Zhang, Dong Zhang, Ning Zhang, Hui Zhou, Jing Zhou, Pengfei Zhou
• Ngôn ngữ: eng
• Thông tin xuất bản: England : Organic & biomolecular chemistry , 2025
• Bộ sưu tập: NCBI
• ID: 190428

Tóm tắt

A novel palladium-catalyzed allylic C-H alkylation of terminal olefins with 3-carboxamide oxindoles is described. A variety of new 3-carboxamide-3-allylation oxindoles with an all-carbon quaternary center were obtained in moderate to good yields (up to 99%). In addition, the asymmetric version of this reaction was also explored, providing moderate enantioselectivity.