The 'inflammazone' in chronic inflammatory diseases: psoriasis and sarcoidosis.

• Tác giả: Phei Er Saw, Erwei Song
• Ngôn ngữ: eng
• Ký hiệu phân loại: 636.0885 Animal husbandry
• Thông tin xuất bản: England : Trends in immunology , 2025
• Bộ sưu tập: NCBI
• ID: 191156

Tóm tắt

Chronic inflammatory diseases show significant heterogeneity in their phenotypes, with diverse immune cells and mediators interacting in response to various stimuli. This review proposes the concept of the 'inflammazone' framework - which maps the distribution of immune components driving disease pathogenesis - using sarcoidosis and psoriasis as examples. Sarcoidosis features granulomatous inflammation with macrophages and CD4