Precision engineering of the probiotic

• Tác giả: Pei-Ru Chen, Xin Li, Shu-Guang Wang, Ying Wei, Peng-Fei Xia, Hai-Yan Yu, Xian-Zheng Yuan
• Ngôn ngữ: eng
• Ký hiệu phân loại: 627.12 Rivers and streams
• Thông tin xuất bản: United States : Applied and environmental microbiology , 2025
• Bộ sưu tập: NCBI
• ID: 191306

Tóm tắt

CRISPR-Cas systems are transforming precision medicine with engineered probiotics as next-generation diagnostics and therapeutics. To promote human health and treat disease, engineering probiotic bacteria demands maximal versatility to enable non-natural functionalities while minimizing undesired genomic interferences. Here, we present a streamlined prime editing approach tailored for probiotic