Transcytosis-Triggering Nanoparticles for Overcoming Stromal Barriers and Reversing Immunosuppression in Pancreatic Cancer Combinatorial Therapy.

• Tác giả: Qinjun Chen, Yun Chen, Hongrui Fan, Mingzhu Fang, Yun Guo, Ru Jia, Chen Jiang, Xuwen Li, Haolin Song, Boyu Su, Tao Sun, Zonghua Tian, Yu Wang, Yuxing Wu, Haoyu You, Shilin Zhang, Zhenhao Zhao, Zheng Zhou
• Ngôn ngữ: eng
• Ký hiệu phân loại: 594.38 *Pulmonata
• Thông tin xuất bản: United States : Nano letters , 2025
• Bộ sưu tập: NCBI
• ID: 192875

Tóm tắt

In pancreatic ductal adenocarcinoma (PDAC), stromal cells and matrix proteins form a dense physical barrier that, while preventing the outward spread of tumor cells, also limits the penetration of drugs and CD8