Design, Synthesis, and Biological Evaluation of Novel Aryl Sulfonamide Derivatives as Potential Succinate Dehydrogenase Inhibitors Targeting Phytopathogenic Fungi.

• Tác giả: Xihao Chang, Yao Chen, Jie Gao, Yamin Huang, Xianhai Lv, Yaping Song, Dandan Wang, Yu Zhang
• Ngôn ngữ: eng
• Ký hiệu phân loại: 220.4047 Original texts, early versions, early translations
• Thông tin xuất bản: United States : Journal of agricultural and food chemistry , 2025
• Bộ sưu tập: NCBI
• ID: 193558

Tóm tắt

In our pursuit of novel succinate dehydrogenase inhibitor (SDHI) fungicides for agriculture, we replaced the traditional amide structure with a sulfonamide framework and introduced various heterocyclic and aromatic rings at the sulfonamide's termini. This strategy yielded 30 synthesized compounds, which were screened for antifungal activity against eight phytopathogenic fungi. The biological assay results demonstrated that several target compounds exhibited significant