BACKGROUND: With advances in the treatment of heart failure with reduced ejection fraction (HFrEF), the prediction of left ventricular reverse remodeling (LVRR) has become increasingly important. Cardiopulmonary exercise testing (CPET) is a non-invasive test recommended for prognostic risk assessment in HFrEF
however, it is not known whether it predicts LVRR. We aimed to investigate whether the parameters obtained from CPET are useful in predicting LVRR in HFrEF. METHODS: We retrospectively evaluated 230 consecutive patients with HFrEF [left ventricular ejection fraction (LVEF) ≤40 %] hospitalized for acute heart failure (59 ± 14 years, 78 % males) who underwent CPET before discharge. We investigated whether the CPET parameters, peak oxygen consumption (VO RESULTS: Among 230 patients, 89 (39 %) exhibited LVRR. In multivariable logistic analysis, higher peak VO CONCLUSIONS: CPET is a valuable test for the non-invasive detection of LVRR. The combination of peak VO