Representing brain-behavior associations by retaining high-motion minoritized youth.

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Tác giả: Arielle Baskin-Sommers, Damien A Fair, Eric Feczko, Clare Kelly, Jivesh Ramduny, Lucina Q Uddin, Tamara Vanderwal

Ngôn ngữ: eng

Ký hiệu phân loại: 617.481 +Brain

Thông tin xuất bản: United States : Biological psychiatry. Cognitive neuroscience and neuroimaging , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 193744

BACKGROUND: Population neuroscience datasets provide an opportunity for researchers to estimate reproducible effect sizes for brain-behavior associations because of their large sample sizes. However, these datasets undergo strict quality control to mitigate sources of noise, such as head motion. This practice often excludes a disproportionate number of minoritized individuals. METHODS: We employ motion-ordering and motion-ordering+resampling (bagging) to test if these methods preserve functional MRI (fMRI) data in the Adolescent Brain Cognitive Development RESULTS: Black and Hispanic youth exhibited excess head motion relative to data collected from White youth, and were discarded disproportionately when using conventional approaches. Motion-ordering and bagging methods retained more than 99% of Black and Hispanic youth. Both methods produced reproducible brain-behavior associations across low-/high-motion racial/ethnic groups based on motion-limited fMRI data. CONCLUSIONS: The motion-ordering and bagging methods are two feasible approaches that can enhance sample representation for testing brain-behavior associations and result in reproducible effect sizes in diverse populations.
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