Identification and characterization of the absorbed components and metabolites of Gandouling tablets in rats' plasma, liver, and urine by UPLC-Q-TOF-MS

• Tác giả: Shijian Cao, Ting Dong, Tiantian Wang, Hongfei Wu, Peng Wu, An Zhou, Qing Zuo
• Ngôn ngữ: eng
• Ký hiệu phân loại: 304.663 Genocide
• Thông tin xuất bản: Netherlands : Journal of chromatography. B, Analytical technologies in the biomedical and life sciences , 2025
• Bộ sưu tập: NCBI
• ID: 19562

Tóm tắt

Gandouling (GDL), a famous proprietary Chinese medicine, has been utilized in China's clinics for decades to treat Wilson's disease. However, its metabolism in vivo needs to be clarified. In this study, Ultra Performance Liquid Chromatography-quadrupole time-of-flight mass spectrometry-tandem (UPLC-Q-TOF-MS