Exploratory high b value diffusion-weighted MR for quantitative differentiation of ileocecal inflammatory conditions and tumors.

• Tác giả: Yucheng Hai, Jingyu Lu, Hao Yu
• Ngôn ngữ: eng
• Ký hiệu phân loại: 230.071 Education in Christianity, in Christian theology
• Thông tin xuất bản: Germany : Insights into imaging , 2025
• Bộ sưu tập: NCBI
• ID: 196565

Tóm tắt

OBJECTIVES: To explore the quantitative analysis of high b value (2000 s/mm METHODS: Sixty-six patients with 30 tumors and 36 inflammatory conditions underwent MR enterography with conventional and high b values DWI. Quantitative apparent diffusion coefficient (ADC) values and signal intensity ratios (SIRs) of lesions of the psoas muscle were measured from the two b value DWIs. The receiver operating characteristic (ROC) curve was applied to determine the diagnostic value of ADC and SIR for differentiating tumors from inflammatory conditions. RESULTS: The ADC values of tumors were significantly lower than those of inflammatory conditions in 800 s/mm CONCLUSIONS: Quantitative ADC values and SIR could be used as non-invasive tools to distinguish ileocecal tumors from inflammatory conditions. The use of high b value DWI would improve this ability. Furthermore, SIR obtained from high b value DWI was the most promising quantitative parameter. CRITICAL RELEVANCE STATEMENT: This study indicated that quantitative DWI parameters might be applied as non-invasive imaging biomarkers for distinguishing bowel tumors from inflammatory conditions. The SIR from high b value DWI could improve the differentiation, providing invaluable information for establishing appropriate therapeutic strategies. KEY POINTS: Differentiation between bowel inflammatory conditions and tumors is still a dilemma. Quantitative DWI contributed to distinguishing ileocecal tumors from inflammatory conditions. SIR from DWI is a promising parameter for differentiating these pathologies.