This paper proposes semi-instrumental variables (semi-IVs) as a practical alternative to instrumental variables (IVs) to identify the causal effect of a binary (or discrete) endogenous treatment. A semi-IV is a less restrictive form of instrument: it affects the selection into treatment but is excluded only from one, not necessarily both, potential outcomes. Having two semi-IVs, one excluded from the potential outcome under treatment and the other from the potential outcome under control, is sufficient to nonparametrically point identify local average treatment effect (LATE) and marginal treatment effect (MTE) parameters. In practice, semi-IVs provide a solution to the challenge of finding valid IVs because they are easier to find: most selection-specific shocks, policies, costs, or benefits are valid semi-IVs. As an application, I estimate the returns to working in the manufacturing sector using sector-specific semi-IVs.