To compare the performance of two contrast agents, barium sulfate and lipiodol, in the performance of 3D CT-DCG. A prospective interventional radiological study was performed on 15 lacrimal drainage systems of 14 patients who clinically presented with nasolacrimal duct obstructions. All patients underwent CT-DCG, traditionally first using lipiodol and a week later by barium sulfate. CT-DCG data was used to construct 3D models as per standard published protocols. A 3D software was used to calculate the volume (which reflects the filling ability of the dye) and the number of details (counted by the number of different faces creating the object) of the 3D CT-DCG of the studied lacrimal drainage systems. The analysis was performed in R, version 4.3.2. The overall mean volume of the dye (filling feature) in the 3D CTDCG reconstructed models of the lacrimal system following lipiodol injection was 55.2 mm