Serum Ferritin Levels in Pregnancy and Their Association with Gestational Diabetes Mellitus: A Prospective Longitudinal Study.

• Tác giả: Yao Du, Bo Huang, Lei Mo, Xianfeng Qin, Zhenhua Qin, Zidi Wang, Hongchi Wu, Xiangyuan Yu, Chaochao Zhao
• Ngôn ngữ: eng
• Ký hiệu phân loại: 152.46 Fear
• Thông tin xuất bản: New Zealand : Diabetes, metabolic syndrome and obesity : targets and therapy , 2025
• Bộ sưu tập: NCBI
• ID: 197156

Tóm tắt

OBJECTIVE: Elevated serum ferritin (SF) levels are associated with oxidative stress (OS) and systemic inflammation in various disorders. However, the changes in SF levels during pregnancy and their relationship with gestational diabetes mellitus (GDM) and blood glucose levels are not well understood. METHODS: This prospective longitudinal study included 390 participants (130 GDM cases and 260 controls) during early pregnancy. We measured SF levels in the1 RESULTS: SF levels decreased with increasing gestation in the study population. Compared to controls, GDM patients had significantly higher levels of SF (1 CONCLUSION: SF is significantly associated with GDM and may be a potential biomarker for GDM in early pregnancy.