BACKGROUND: The incidence of nosocomial candidemia has increased in recently years, however, the epidemiological data remain insufficient in China. METHODS: A total of 234 candidemia patients were included from Xiamen University Zhong Shan hospital between January 2006 and October 2024. Incidence, species proportion, distribution, antifungal drug resistance of candidemia was analyzed. A nomogram model for 30-day morbidity of candidemia was determined using the least absolute shrinkage and logistic regression analysis. RESULTS: The incidence of candidemia increased in recent years (2020: 0.025%, 2021: 0.029%, 2023:0.022%). The dominant species of candidemia were CONCLUSION: The incidence of nosocomial candidemia has risen in recent years.