Metabolite pathway alterations identified by magnetic resonance metabolomics in a proximal tubular epithelial cell line treated with TGF-β1.

• Tác giả: Ross S Francis, Graham J Galloway, Glenda C Gobe, Tyrone L R Humphries, Andrew J Kassianos, Soobin Lee, Aaron S Micallef, Aaron J Urquhart, David A Vesey, Clay Winterford
• Ngôn ngữ: eng
• Ký hiệu phân loại: 538.36 Magnetic resonance
• Thông tin xuất bản: United States : Physiological reports , 2025
• Bộ sưu tập: NCBI
• ID: 197832

Tóm tắt

Tubulointerstitial fibrosis is a characteristic hallmark of chronic kidney disease (CKD). Metabolic perturbations in cellular energy metabolism contribute to the pathogenesis of CKD, but the chemical contributors remain unclear. The aim of this investigation was to use two dimensional