Choice of Drug for Malaria Prevention During Pregnancy Does Not Affect Infant Serologic Responses to

• Tác giả: Matthew Adams, Liana R Andronescu, Jobiba Chinkhumba, Philip L Felgner, Aarti Jain, Algis Jasinskas, Miriam K Laufer, Don P Mathanga, Rie Nakajima, Amed Ouattara, Ankur Sharma, Omid Taghavian, Mark A Travassos
• Ngôn ngữ: eng
• Ký hiệu phân loại: 025.322 *Choice of entry and form of heading
• Thông tin xuất bản: United States : Open forum infectious diseases , 2025
• Bộ sưu tập: NCBI
• ID: 197985

Tóm tắt

While sulfadoxine-pyrimethamine has been the primary drug in intermittent preventive treatment in pregnancy, dihydroartemisinin-piperaquine (DP) is being considered as an alternative. DP may lead to lower antimalarial antibodies in the mother, resulting in higher risk of malaria in infancy. We probed cord blood sera collected from women enrolled in a clinical trial of sulfadoxine-pyrimethamine vs DP on a protein microarray containing diverse