The determination of curcumin (CM), the active ingredient of turmeric, can be used to control the quality of turmeric rhizomes and products. A CM sensor was developed based on a nitrogen and sulfur dual-doped laser-induced graphene (N-S@LIG) material fabricated in the form of a three-electrode system on a polyethylene terephthalate (PET) substrate. N-S@LIG was synthesized by the one-step laser ablation of a polyimide (PI) carbon source coated with a methylene blue (MB) N and S source. The surface morphology of the fabricated electrode was studied by scanning electron microscopy, energy dispersive x-ray analysis, Raman spectroscopy, contact angle analysis, and X-ray photoelectron spectroscopy. The electrode showed an excellent electron transfer ability and good electrocatalytic performances for the detection of CM. The N and S dual-doped laser-induced graphene electrode (N-S@LIGE) was employed to determine CM by differential pulse adsorptive stripping voltammetry (DPAdSV). To enable on-site analysis of CM in turmeric samples, the N-S@LIGE was incorporated with a small potentiostat plugged into a smartphone to manage the measurements and to display results. The developed CM sensor displayed a linear determination range from 0.10 to 30 μmol L