Circulating Tumor Cells: Finding Rare Events for A Huge Knowledge of Cancer Dissemination

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Tác giả: Catherine Alix-Panabieres

Ngôn ngữ: eng

ISBN-13: 978-3039286980

Ký hiệu phân loại:

Thông tin xuất bản: Basel, Switzerland : MDPI - Multidisciplinary Digital Publishing Institute, 2020

Mô tả vật lý: 1 electronic resource (366 p.)

Bộ sưu tập: Tài liệu truy cập mở

ID: 201791

 The analysis of circulating tumor cells (CTCs) as a real-time liquid biopsy approach can be used to obtain new insights into metastasis biology, and as companion diagnostics to improve the stratification of therapies and to obtain insights into the therapy-induced selection of cancer cells. In this book, we will cover all the different facets of CTCs to assemble a huge corpus of knowledge on cancer dissemination: technologies for their enrichment, detection, and characterization
  their analysis at the single-cell level
  their journey as CTC microemboli
  their clinical relevance
  their biology with the epithelial-to-mesenchymal transition (EMT)
  their stem-cell properties
  their potential to initiate metastasis at distant sites
  their ex vivo expansion
  and their escape from the immune system.
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