This book consists of seven chapters containing multiple questions of the global socially epistemological situation in science and higher education. Despite the progress of techno-sciences, we are facing blind flaws in leading systems of knowledge and perception. The global era, in a paradox way, connects the new knowledge of economics, postpolitics, postdemocracy, and biopolitical regulation of live and unpresentable forms of the global geo-located violence. Techno-optimism and techno-dictatorship in the twenty-first century coincide with the ideology of market, biopolitics of mandatory satisfaction, religious revivalism, and collapse of higher education. In order for sciences to recover, it is necessary to make a globally epistemological and moral turn toward the truth. The book shows that, when joint desires of the new economics of knowledge and technology erase epistemology (in a way to assign definitions of knowledge and rules and practices of the public usage of the mind), then the time for epistemology is on its way.