Ethanol, Its Active Metabolites, and Their Mechanisms of Action: Neurophysiological and Behavioral Effects

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Tác giả: Elio Acquas, John D. Salamone, Mercè Correa

Ngôn ngữ: eng

ISBN-13: 978-2889455164

Ký hiệu phân loại:

Thông tin xuất bản: Frontiers Media SA, 2018

Mô tả vật lý: 1 electronic resource (184 p.)

Bộ sưu tập: Tài liệu truy cập mở

ID: 202749

Ethanol, the main psychopharmacologically active ingredient of alcoholic drinks, represents a paradigmatic example of a research subject intrinsically able to perpetually self-generate interdisciplinary cutting-edge investigations. This eBook was inspired by the aim of providing an up-to-date characterization of the diverse effects of ethanol, of the possible mechanisms of action on different intracellular systems as well as of the hypothesized actions of ethanol and/or its metabolites on various neurotransmitters and neuromodulators. Indeed, the eBook provides a factual example of an excellent synthesis on the complex relationship between ethanol and its main biologically active metabolites (
- Chapter 1), on the behavioral and molecular consequences of early exposure to them (
- Chapter 2), on the recent proposals, advanced by the preclinical research, for new therapeutic approaches to distinct aspects of alcoholism (
- Chapter 3) and on the most recent and original preclinical evidence of the interactions between ethanol and/or its metabolites and the dopaminergic, adenosinergic and endocannabinoidergic systems (
- Chapter 4). Overall we believe that this eBook accomplishes its main goals of widening the perspective on this research subject and offering the readership a newer and, simultaneously, up-to-date and comprehensive scenery on ethanol's and ethanol's active metabolites neurophysiological and behavioral effects.
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