The anatomical deformation in cleft patients requires speech therapy to support cleft patients as best as possible. The aim of this study was to evaluate the standard of knowledge of therapists concerning clefts. Furthermore, the study aimed to determine whether there was a difference between therapists with and without treatment experience in cleft patients as well as among therapists with more or less years of general professional experience. We developed a questionnaire about different areas of speech therapy: "General," "Speech therapy," "Development opportunities and influences," and "Interdisciplinary collaboration." For a total of 50 questions, we used single-, multiple-choice questions and the visual analog scale (VAS). Speech therapists with experience in treating cleft patients (n = 43) felt more confident regarding their knowledge and abilities than therapists without experience (n = 61), especially concerning nonspecialist disciplines and cleft specifications. No difference was found in therapy duration, indications, influences, and potential for development. Professional experience (years) and cleft experience correlate
with more knowledge in the group with more than 8 years of experience. Cleft centers remain first choice for patients' care thanks to the higher number of patients, daily treatment routine, the direct contact among examiners, and a common treatment concept.