Tandem-controlled lysosomal assembly of nanofibres induces pyroptosis for cancer immunotherapy.

• Tác giả: He Bai, Zhiyuan Feng, Yuxuan Hu, Jie Li, Yinxing Miao, Ling Qiu, Tian Tian, Ziyi Wang, Xidan Wen, Jing-Juan Xu, Qi Xue, Zeyue Yang, Deju Ye, Jingjing Zhang, Junya Zhang, Peng Zheng
• Ngôn ngữ: eng
• Thông tin xuất bản: England : Nature nanotechnology , 2025
• Bộ sưu tập: NCBI
• ID: 204929

Tóm tắt

Pyroptosis has emerged as a promising approach for cancer immunotherapy. However, current pyroptosis inducers lack specificity for cancer cells and have a weak antitumour immune response. Here we report a tumour-specific nanoparticle (NP-NH-D