The ability to create intelligent machines has intrigued humans since ancient times, and today with the advent of the computer and 50 years of research into AI programming techniques, the dream of smart machines is becoming a reality. The concept of human-computer interfaces has been undergoing changes over the years. In carrying out the most important tasks is the lack of formalized application methods, mathematical models and advanced computer support. The evolution of biological systems to adapt to their environment has fascinated and challenged scientists to increase their level of understanding of the functional characteristics of such systems. This book has 19 chapters and explain that the expert systems are products of the artificial intelligence, branch of computer science that seeks to develop intelligent programs for human, materials and automation.