Anticoagulation Therapy

• Tác giả: Ozcan Basaran, Murat Biteker
• Ngôn ngữ: eng
• ISBN-13: 978-9535173090
• Ký hiệu phân loại: 780.924 Music
• Thông tin xuất bản: Croatia : IntechOpen, 2016
• Mô tả vật lý: 1 electronic resource (150 p.)
• Bộ sưu tập: Tài liệu truy cập mở
• ID: 207497
• Chủ đề: 1. Pharmacology

Tóm tắt

The available parenteral and oral anticoagulants have a large clinical use. Understanding biochemistry of anticoagulants may help to improve therapeutic strategies. Resistance to vitamin K antagonist drugs might be a problem for rodent populations. Patients who have thrombogenic risk factors should be anticoagulated. The need for cardiac implantable electronic devices is increasing, and there is a substantial number of patients who are on oral anticoagulant therapy. Prothrombin complex concentrate and other plasma concentrates are useful to deal with over-coagulated situations. The efficacy and safety of non-vitamin K antagonist oral anticoagulants have been proven in large phase III trials. The real-world data suggest even better outcomes with these agents compared to vitamin K antagonists.