The Effect of Calorie Restriction and Intermittent Fasting on Health and Disease

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Tác giả: Hae-Young Chung

Ngôn ngữ: eng

ISBN-13: 978-3039438372

Ký hiệu phân loại:

Thông tin xuất bản: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021

Mô tả vật lý: 1 electronic resource (186 p.)

Bộ sưu tập: Tài liệu truy cập mở

ID: 208463

Recent biochemical studies indicate that calorie restriction (CR) is a widely accepted method for anti-aging intervention. CR and intermittent fasting (IF), which involves reduced calories but proper nutritional intake during specific periods, are interventions that can consistently promote health benefits, delay biological aging, and extend both average and maximal lifespan. Furthermore, CR can modulate age-related diseases such as Alzheimer's disease, atherosclerosis, diabetes, obesity, cancer, and others. Advances in omics technologies have provided a technical breakthrough that enabled the investigation of DNA, RNA, proteins, and other cellular molecules and their comprehensive interactions in a biological context. Nowadays, it is possible to analyze and integrate biological processes that occur in aging systems at the molecular level using state-of-the-art techniques such as next-generation sequencing (NGS), proteomics, lipidomics, metabolomics, and epigenomics. Omics technology and systems gerontology provide predictive information on CR effects, molecular mechanisms, and pathways underlying the anti-aging actions of CR and IF. This Special Issue, "The effects of calorie restriction and intermittent fasting on health and disease", focuses on the effects of calorie restriction and intermittent fasting on age-related inflammation, autophagy, metabolism, longevity, mitochondrial function, and age-related diseases.
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