Novel Heterocyclic Piperazine Amide Derivatives as Alpha-synuclein PET Ligands for Diagnosis of Parkinson's Disease.

• Tác giả: Yinlong Li, Steven H Liang
• Ngôn ngữ: eng
• Ký hiệu phân loại: 332.6457 Investment
• Thông tin xuất bản: United States : ACS medicinal chemistry letters , 2025
• Bộ sưu tập: NCBI
• ID: 209724

Tóm tắt

This Patent Highlight describes novel substituted heterocyclic piperazine amide compounds and their isotopically labeled derivatives. These compounds are designed as promising positron emission tomography (PET) ligands targeting alpha-synuclein, offering potential for the diagnosis of neurodegenerative disorders, including Parkinson's disease.