The role of N(6)-methyladenosine (m6a) modification in cancer: recent advances and future directions.

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Tác giả: Feng Cao, Zhen Fang, Yuchen Jia, Fei Li, Jie Li, Liang Shang, Zheng Wang, Xiaozhou Xie, Haoyu Zhang

Ngôn ngữ: eng

Ký hiệu phân loại: 305.568 +Alienated and excluded classes

Thông tin xuất bản: Germany : EXCLI journal , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 210507

Thêm vào giỏ Liên kết toàn văn

N(6)-methyladenosine (m6A) modification is the most abundant and prevalent internal modification in eukaryotic mRNAs. The role of m6A modification in cancer has become a hot research topic in recent years and has been widely explored. m6A modifications have been shown to regulate cancer occurrence and progression by modulating different target molecules. This paper reviews the recent research progress of m6A modifications in cancer and provides an outlook on future research directions, especially the development of molecularly targeted drugs. See also the graphical abstract(Fig. 1).

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