Knockdown of EBP1 promotes doxorubicin-induced apoptosis in renal clear cell carcinoma cells through activation of the p38/HIF-1α pathway.

• Tác giả: Shuxia Cao, Jiaqi Huo, Xiangdan Li, Lan Liu, Lina Ma, Shengri Tian, Yuyang Yue
• Ngôn ngữ: eng
• Ký hiệu phân loại: 959.3031 *Thailand
• Thông tin xuất bản: Greece : Oncology letters , 2025
• Bộ sưu tập: NCBI
• ID: 210896

Tóm tắt

Kidney clear cell carcinoma (KIRC) is a prevalent urological cancer. Despite substantial improvements in KIRC care, patients with intermediate and advanced stages of the disease lack access to appropriate medications. Doxorubicin is widely used as a chemotherapy drug for the treatment of multiple types of cancer. However, its use is associated with harmful side effects and drug resistance. ErbB3-binding protein (