Application of cellular microstructural diffusion MRI (cell size imaging) in rectal lesions: a preliminary study.

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Tác giả: Jingliang Cheng, Peisi Kou, Juan Li, Ying Li, Liangjie Lin, Hui Qin, Kun Zhang, Wenhua Zhang, Yong Zhang

Ngôn ngữ: eng

Ký hiệu phân loại: 912.01 Philosophy and theory

Thông tin xuất bản: Switzerland : Frontiers in oncology , 2025

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Bộ sưu tập: NCBI

ID: 211537

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OBJECTIVES: To explore the value of cellular microstructural mapping by IMPULSED (imaging microstructural parameters using limited spectrally edited diffusion) method in evaluating the histological type and prognostic factors of rectal lesions. MATERIALS AND METHODS: Sixty-six patients with rectal lesions were enrolled in this study. All subjects underwent MRI scans including conventional diffusion weighted imaging (DWI) and the IMPULSED MRI scans of oscillating gradient spin-echo (OGSE) and pulse gradient spin-echo (PGSE) sequences. Parameters including mean cell diameter (d RESULTS: Our preliminary results illustrated that malignant lesion showed higher v CONCLUSION: Cellular microstructural mapping by the IMPULSED method has great potential in preoperative evaluation of rectal lesions. It could be helpful in differentiating malignant and benign lesions, distinguishing AC from MC, and in predicting the TB status.

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