Germ Cell Neoplasia

• Tác giả: Aditya Arvind Manekar, Pravash Ranjan Mishra, Suvendu Purkait, Bikasha Bihary Tripathy
• Ngôn ngữ: eng
• Ký hiệu phân loại: 912.01 Philosophy and theory
• Thông tin xuất bản: India : Journal of Indian Association of Pediatric Surgeons , 2025
• Bộ sưu tập: NCBI
• ID: 212807

Tóm tắt

BACKGROUND: Untreated cryptorchid testes are in risk of intratubular germ cell neoplasia and subsequently may give rise to invasive germ cell tumors. MATERIALS AND METHODS: Tissue samples were obtained from patients undergoing orchidectomy or orchiopexy and were subjected to routine histopathological and immunohistochemical examinations. RESULTS: Forty-three patients were enrolled in this study out of which 30 samples were collected. The mean age of patients was 9.16 years. One case (6.7%) showed positivity of the germ cell neoplasia with anto placental alkaline phosphatase and Anto CD-117 positive. Other histopathological findings such as fibrocollagenous tissue and Leydig cell hyperplasia were reported. CONCLUSION: Early surgical management is of importance for a better outcome in cases of undescended testes.