The geodatabase on weather-related disasters in agriculture is a part of the cloud storage which hosts the materials of the Observatory for Agricultural meteorology and climatology of the Council for Agricultural Research and Economics (CREA). A specific relational SQL geodatabase has been created by data entry from the official decrees of disaster declaration of the Italian Ministry of Agriculture, food sovereignty and forests within the "National Solidarity Fund for natural disasters in agriculture" (Italian law d.lgs. 102/2004). From this database, managed by CREA for internal research purposes, a dataset has been extracted for the period from 2005 to 2021 and published in the Zenodo repository in text format (.csv file) annotated with discovery and structural metadata. The dataset aims to make available useful data for weather-related risk assessment in agriculture and for agrometeorological analyses of extreme weather events leading to disasters. The following types of weather-related disasters in agriculture are included in the dataset: drought, excess of snow, frost, hail, heat stress, heavy rain leading to flood, persistent rain, tornado, strong wind and sirocco wind. The dataset will be periodically updated.