Insulin autoimmune syndrome (IAS) is a known cause of hypoglycemia, more commonly observed in Asian populations, but it is rarely seen in Western countries. We present a case of recurrent hypoglycemia in a 53-year-old Caucasian female, attributed to insulin autoantibodies, which responded well to treatment with steroids and dietary modifications. Increasing awareness of IAS among clinicians is crucial to prevent unnecessary, costly, and potentially harmful diagnostic procedures when investigating recurrent and refractory hypoglycemia, and to ensure appropriate management strategies are implemented.