Multifunctional liposome boosts glioma ferroptosis and immunotherapy through reinforcement of chemo-dynamic therapy strategy.

• Tác giả: Hongwu Chen, Jieling Chen, Tingting Deng, Cong Huang, Jiehao Huang, Rui Lin, Zhongjing Su, Huaiming Wang, Jie Wu, Yimin Xu
• Ngôn ngữ: eng
• Ký hiệu phân loại: 553.3 Iron
• Thông tin xuất bản: England : Materials today. Bio , 2025
• Bộ sưu tập: NCBI
• ID: 213581
• Chủ đề: 1. Multifunctional; 2. Liposome; 3. Boosts

Tóm tắt

Glioma remains significant challenging to completely cure by the conventional surgical resection because of its high infiltrative growth properties. Recently, emerging immunotherapy has achieved remarkable success in treating various cancer, but glioma do not benefit from cancer immunotherapy owing to its specific immunosuppressive tumor microenvironment (iTME). Herein, we show the significant improvement of the immunotherapy efficacy for glioma through multifunctional liposome (Lpo@Cu