Halophytes are plants adapted to saline soils found in a diversity of environments with varied climatic conditions and high salinity, developing different strategies to complete their life cycle. Their ecological, morphological, physiological and biochemical adaptations allow resistance to the abiotic stresses suffered and the formation of bioactive compounds that give these plants anti-inflammatory, antiparasitic, antimicrobial, antiviral and antioxidant potential properties. Therefore, this study aimed to compile its different biological activities, its nutritional compounds, potential applications for pharmaceutical and food industries, its biotechnological use. Halophytes have vast potential for pharmaceutical industries, as well as being a sustainable alternative in production of animal feed and a viable possibility for replacing the use of table salt and its various applications in human nutrition. It is necessary to invest in new and diversified research highlighted in this study.