Protosequences in brain organoids model intrinsic brain states Authors.

• Tác giả: Dowlette-Mary Alam El Din, Julian Bartram, Kiran Bhaskaran-Nair, Lon J Blauvelt, Mattia Chini, Bradley M Colquitt, Aditya Dendukuri, Cole Duncan, Jinghui Geng, Jesus Gonzalez-Ferrer, Ileana L Hanganu-Opatz, Paul K Hansma, Cole R K Harder, Keith B Hengen, Sebastian Hernandez, Andreas Hierlemann, Gregory A Kaurala, Kenneth S Kosik, Jason Laird, Max Lim, Sawyer McKenna, Mohammed A Mostajo-Radji, Linda R Petzold, Maren Schenke, Hunter E Schweiger, Tal Sharf, Lena Smirnova, Alex Spaeth, Mircea Teodorescu, Tjitse van der Molen, Zongren Zhang
• Ngôn ngữ: eng
• Ký hiệu phân loại: 636.0885 Animal husbandry
• Thông tin xuất bản: United States : bioRxiv : the preprint server for biology , 2025
• Bộ sưu tập: NCBI
• ID: 214905

Tóm tắt

Neuronal firing sequences are thought to be the basic building blocks of neural coding and information broadcasting within the brain. However, when sequences emerge during neurodevelopment remains unknown. We demonstrate that structured firing sequences are present in spontaneous activity of human and murine brain organoids and