Designed endocytosis-inducing proteins degrade targets and amplify signals.

• Tác giả: Mohamad Abedi, Maggie Ahlrichs, Green Ahn, David Baker, Nathaniel R Bennett, Gonçalo J L Bernardes, Carolyn R Bertozzi, Longxing Cao, Lauren Carter, Sidney Chan, Adam Chazin-Gray, Ching Wen Chiu, Brian Coventry, Craig Dobbins, Maria J Duran Gonzalez, Stacey Gerben, Inna Goreshnik, Per Jr Greisen, Buwei Huang, Xiaochun Li, Ayesha Misquith, Rubul Mout, Analisa Murray, Jason O'Neill, Dan I Piraner, Kole T Roybal, Danny D Sahtoe, Isaac Sappington, Thomas Schlichthaerle, Shirin Shivaei, Jamie B Spangler, Lance Stewart, Cong Tang, Luke M Tomasovic, Dionne Vafeados, Preetham Venkatesh, Rong Wang, Shunzhi Wang, Xinru Wang, Yujia Wang, Anitra Wolf, Wei Yang, Ronald Yeh, Li Yi, Jason Z Zhang
• Ngôn ngữ: eng
• Ký hiệu phân loại: 943.1087 *Northeastern Germany
• Thông tin xuất bản: England : Nature , 2025
• Bộ sưu tập: NCBI
• ID: 215373

Tóm tắt

Endocytosis and lysosomal trafficking of cell surface receptors can be triggered by endogenous ligands. Therapeutic approaches such as lysosome-targeting chimaeras