BACKGROUND: Although intravenous thrombolysis (IVT) is safe and effective in populations with general stroke, its impact on cervical artery dissection-related acute ischemic stroke (CeAD-AIS) remains unclear. This retrospective study used the National Inpatient Sample to compare outcomes in patients with CeAD-AIS treated with and without IVT. METHODS: We included adult patients with concurrent CeAD and AIS diagnoses ( RESULTS: Between 2016 and 2019, 1360 (12.1%) of 11 285 patients with CeAD-AIS received IVT. IVT-treated patients had higher median National Institutes of Health Stroke Scale scores (median [interquartile range], 8 [4-17] versus 3 [1-11]
CONCLUSIONS: IVT improves the likelihood of home discharge in patients with CeAD-AIS without increasing the risk of inpatient death or intracerebral hemorrhage.