BACKGROUND: Barbed sutures eliminate knots and may offer some advantages over conventional sutures. This meta-analysis compares clinical, surgical, and economic outcomes of barbed sutures with standard closure techniques in spinal surgery. METHODS: We systematically searched PubMed, Embase, and Web of Science for studies comparing barbed and conventional suture for patients undergoing spinal surgery. RESULTS: We included 6 studies in the analysis, totaling 1235 patients. There was no significant difference between the groups in relation to deep infection (risk ratio [RR] 0.65
95% confidence interval [CI]: 0.26-1.57
I CONCLUSIONS: Our meta-analysis showed that barbed sutures were associated with reduced operating room time, suturing time, and infection rates. These results highlight the safety and potential efficacy of using barbed sutures.