Functional heterogeneity of endothelium-dependent vasorelaxation in different order branches of mesenteric artery in female/male mice.

• Tác giả: Hui Dong, Shaoya Rong, Luyun Zhang
• Ngôn ngữ: eng
• Ký hiệu phân loại: 553.453 Tin
• Thông tin xuất bản: United States : Microvascular research , 2025
• Bộ sưu tập: NCBI
• ID: 216278

Tóm tắt

 Although the mouse mesenteric artery is widely used as a model of resistance vessels, it is unknown which order branch is the best representative and if there is a heterogeneity of vascular activity in different orders. We systematically compared the vasorelaxation between the mouse mesenteric artery's first- and second-order branches. The first- and second-order branches of the mesenteric artery (lumen diameter of >
 300 μm and 179.9 ± 11.1 μm, respectively) were taken from the location close to their branching points in wide-type (WT) and TRPV4