Exploring high molecular weight components in Tityus serrulatus venom.

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Tác giả: Nicoly Malachize Alano-da-Silva, Eliane Candiani Arantes, Karla de Castro Figueiredo Bordon, Iara Aimê Cardoso, Isadora Sousa de Oliveira

Ngôn ngữ: eng

Ký hiệu phân loại: 141 Idealism and related systems and doctrines

Thông tin xuất bản: England : Toxicon : official journal of the International Society on Toxinology , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 217194

Our study identified high-molecular-weight compounds from Tityus serrulatus venom (TsV), and most of them have not yet been well explored. TsV was fractionated using FPLC system with different columns, analyzed by SDS-PAGE, and characterized by MALDI-TOF/TOF. Our study showed that TsV contains several high-molecular-weight compounds, including CRISPs, metalloproteinase and hyaluronidase. We show how these molecules can be obtained from TsV, enabling future studies about their molecular structures and biological actions, expanding knowledge about this venom.
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