Derivation of induced pluripotent stem cell FDZSi002-A from a 67-year-old Chinese Han Prostate cancer patient.

• Tác giả: Zhuo Chen, Hao-Yu Cui, Chuan-Sheng Hou, Xue-Qiang Lu, Hao Wu, Xue-Feng Xie, Bei Zhang, Zhe Zhu
• Ngôn ngữ: eng
• Ký hiệu phân loại: 332.63242 Investment
• Thông tin xuất bản: England : Stem cell research , 2025
• Bộ sưu tập: NCBI
• ID: 217709

Tóm tắt

Prostate cancer (PCa) is the most common malignant tumor of the male reproductive system. In this study, we generated an induced pluripotent stem cell (iPSC) line from the peripheral blood mononuclear cells (PBMCs) of a 67-year-old male patient and diagnosed with PC. The established iPSCs were confirmed by flow cytometry and immunofluorescence. Furthermore, the iPSC line has a normal chromosomal karyotype and has the potential of spontaneous differentiation into three germ layers in vitro. The iPSC line will be a useful tool for investigating the pathogenesis mechanisms of PCa.