Tobacco smoke carcinogens exacerbate APOBEC mutagenesis and carcinogenesis.

• Tác giả: Ludmil B Alexandrov, Prokopios P Argyris, Erik N Bergstrom, Marcos Díaz-Gay, Cameron Durfee, Reuben S Harris, Mahmoud A Ibrahim, Xingyu Liu, Shuvro P Nandi, Joshua Proehl, Christopher D Steele, Nuri Alpay Temiz, Rachel I Vogel, Yaxi Wang, Yufan Zhou
• Ngôn ngữ: eng
• Ký hiệu phân loại: 362.296 Tobacco
• Thông tin xuất bản: United States : bioRxiv : the preprint server for biology , 2025
• Bộ sưu tập: NCBI
• ID: 218035

Tóm tắt

Mutations in somatic cells are inflicted by both extrinsic and intrinsic sources and contribute over time to cancer. Tobacco smoke contains chemical carcinogens that have been causatively implicated with cancers of the lung and head & neck