The E2F4 transcriptional repressor is a key mechanistic regulator of colon cancer resistance to

• Tác giả: Russ B Altman, Michael F Clarke, Piero Dalerba, Taichi Isobe, Sanjay Koul, Yong Fuga Li, Junichi Matsubara, Junko Mukohyama, Dalong Qian, Debashis Sahoo, Luis E Valencia Salazar
• Ngôn ngữ: eng
• Ký hiệu phân loại: 271.6 *Passionists and Redemptorists
• Thông tin xuất bản: United States : bioRxiv : the preprint server for biology , 2025
• Bộ sưu tập: NCBI
• ID: 218176

Tóm tắt

METHODS: In this study, we used RESULTS: Our analysis identified E2F4 and TFDP1, two core components of the DREAM transcriptional repression complex, as transcriptional modulators preferentially activated by CONCLUSIONS: Our data identified E2F4 and the DREAM repressor complex as critical regulators of human CRC resistance to