Therapeutic Potential of FTO Demethylase in Metabolism and Disease Pathways.

• Tác giả: Thirunavukarasou Anand, Nagaraj Bharathkumar, Damal Chandrasekar Mathangi, Konda Mani Saravanan, Selvaraj Sathyapriya, Chaitanya Sree Somala
• Ngôn ngữ: eng
• Ký hiệu phân loại: 612.39 Metabolism
• Thông tin xuất bản: Netherlands : The protein journal , 2025
• Bộ sưu tập: NCBI
• ID: 218504

Tóm tắt

The crucial involvement of the Fat Mass and Obesity-associated (FTO) protein in both metabolic and non-metabolic diseases has been documented since its discovery. This enzyme, known as FTO, is a demethylase that belongs to the 2-oxoglutarate-dependent nucleic acid demethylases. Its primary function is to target N6-methyladenosine (m