Empowering canine genomics: design and validation of a high-density SNP array for Indian dogs.

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Tác giả: Sonika Ahlawat, Reena Arora, Mehak Maggon, Raja Kolandanoor Nachiappan, Meenal Raheja, Manisha Sharma, Upasna Sharma, Ramesh Kumar Vijh

Ngôn ngữ: eng

Ký hiệu phân loại: 920.71 Men

Thông tin xuất bản: Canada : Genome , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 218671

India harbors a substantial population of 9.43 million dogs, showcasing diverse phenotypes and utility. Initiatives focusing on awareness, conservation, and informed breeding can greatly enhance the recognition and welfare of the unique Indian canine heritage. This study describes the design and development of a high-density SNP array for genomic characterization of Indian dogs. Paired-end (150 bp) DNA sequences of 48 samples from four diverse dog populations were generated with 10× coverage, following the standard pipeline of Axiom Array technology for chip design. More than 23 million raw SNPs were initially identified, with 629 597 SNP markers ultimately tiled on the Indian canine array (
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