Development and validation of a point-of-care molecular assay for sacbrood virus (SBV) diagnosis in apiaries.

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Tác giả: Doo-Sung Cheon, Nyun-Ki Chung, Juhaeng Heo, Dae-Yong Kim, Yongrae Kim

Ngôn ngữ: eng

Ký hiệu phân loại: 338.9 Economic development and growth

Thông tin xuất bản: Netherlands : Journal of virological methods , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 219180

Sacbrood virus (SBV) is a significant pathogen affecting honeybee health, leading to substantial economic losses in apiculture. Although traditional methods, like reverse transcription quantitative polymerase chain reaction, offer accurate detection and quantification of SBV, they have limitations for use in field settings, such as apiaries. Here, we developed and evaluated the XQ SBV Dx Kit as a diagnostic tool for the XQ Station point-of-care (POC) RT-qPCR device, which integrates nucleic acid extraction, gene amplification, and detection for on-site molecular diagnosis. Diagnostic performance was assessed using clinical samples infected with SBV and was compared with that of standard laboratory-based RT-qPCR. The limit of detection (LOD) for both methods was 10
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