De Novo Production of 1,6-Hexanediol and 1,6-Hexamethylenediamine from Glucose by Metabolic Engineered

• Tác giả: Zhen Chen, Dehua Liu, Youmeng Liu, Nan Qin, Fanghuan Zhu
• Ngôn ngữ: eng
• Thông tin xuất bản: United States : ACS synthetic biology , 2025
• Bộ sưu tập: NCBI
• ID: 219736

Tóm tắt

1,6-Hexamethylenediamine (HMD) and 1,6-hexanediol (HDO) are pivotal C6 platform chemicals with extensive applications as key monomers in the synthesis of nylons, polyurethanes, and polyesters. The biological production of HMD and HDO from cheap and renewable bioresources represents an environmentally benign strategy for the sustainable chemical industry. Herein, we report the development of a novel biocatalytic route for the direct conversion of d-glucose to HMD and HDO in