BACKGROUND: Atrial fibrillation (AF) is the most frequently recorded arrhythmia in clinical practice, and its appearance conditions high risk of morbidity and mortality. The role of interatrial block (IAB) as predictor pathway of the development of AF in the postoperative period of patients undergoing cardiac surgery has been studied scantly. METHODS: Partial IAB was defined as the P wave >
120 ms, and advanced IAB as the P wave >
120 ms with biphasic morphology in inferior leads. The pre-surgical ECG was analyzed and the frequency of AF onset in the postoperative period was determined. A comparative analysis was performed between the patients who presented AF, and those who did not. RESULTS: A total of 94 patients were included, with a mean age of 61±16 years. Of the total number of patients, 42 (45%) presented some degree of IAB (partial 42.8%, advanced 57.1%). There was a significant relationship between patients with IAB and those who develop AF post-cardiac surgery (21.3% p<
0.01). The presence of interatrial block had an [area under the curve, 0.75
95% confidence intervals (CI), 0.66-0.85] and demonstrated a specificity of 69%, a sensitivity of 83%, and negative predictive value of 92% for predicting AF development. CONCLUSION: IAB has a relatively frequent incidence in patients undergoing cardiac surgery. There was a significant association between the presence of IAB and the development of AF in the postoperative period. Our findings establish for the first time that IAB has high specificity, sensitivity, and negative predictive value for predicting AF development post-cardiac surgery.