Research to date has examined telomere length in relation to adverse childhood events but few studies have examined whether protective factors act as a buffer to offset this effect. Further, research is lacking examining whether protective factors vary among minoritized youth. Data were from the Future Families and Child Wellbeing Study, a stratified, multistage sample of 4898 children born in large U.S. cities between 1998 and 2000. Births to unmarried mothers were oversampled by a 3-1 ratio, which resulted in the inclusion of a multi-ethnic and economically diverse sample (48 % Black
27 % Hispanic
21 % White
4 % other racial and ethnic minorities). The current study examined optimism, social connectedness, and neighborhood collective efficacy at age 15 as potential protective factors against the effects of harsh parenting on telomere length in adolescence (analytic N = 1168 youth). This study examines cumulative exposure to harsh parenting across childhood (ages 3, 5, and 9 years). Results from analyses stratified by race/ethnicity show optimism, connectedness, and neighborhood collective efficacy serve as protective factors
however, unique protective factors emerged among different racial and ethnic youth suggesting the need to examine context-specific protective factors. Implications of these findings provide evidence for considering intersectionality in terms of protective factors for biomarkers among minoritized youth.