Is Isochoric Vitrification Feasible?, Cycling Between Modeling, Experimental Observations, and First Principles.

 0 Người đánh giá. Xếp hạng trung bình 0

Tác giả: Yoed Rabin, Prem K Solanki

Ngôn ngữ: eng

Ký hiệu phân loại: 616.963 *Diseases due to flukes (Trematode infections)

Thông tin xuất bản: Netherlands : Cryobiology , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 224197

Isochoric cryopreservation is preservation of biological material in a constant-volume container, to benefit from a presumed baroprotective effect. From its inception, the premise for the isochoric approach is that pressure elevation can be achieved by permitting some ice formation in the system. The idea of integrating vitrification into an isochoric chamber followed at a later stage, where vitrification is a century old established approach of ice-free cryopreservation. At face value, the resulting term "isochoric vitrification" encompasses an internal contradiction revolving around ice formation. We have previously shared modeling results pointing to this contradiction and, hence, questioning the feasibility of the process (Cryobiology 2023, 111, 9-15). More recently, Ali et al. (Cryobiology 2024, 116, 104935) claimed to have obtained contradictory experimental evidence while stating that isochoric vitrification is feasible. The objective for this brief communication is to share our skepticism about this claim with the community of cryobiology.
Tạo bộ sưu tập với mã QR

THƯ VIỆN - TRƯỜNG ĐẠI HỌC CÔNG NGHỆ TP.HCM

ĐT: (028) 36225755 | Email: tt.thuvien@hutech.edu.vn

Copyright @2024 THƯ VIỆN HUTECH