Drug Discovery and Development : New Advances

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Tác giả: Vishwanath Gaitonde, Partha Karmakar, Ashit Trivedi

Ngôn ngữ: eng

ISBN-13: 978-1789239751

ISBN-13: 978-1789239768

ISBN-13: 978-1789852196

ISBN: intechopen.77685

Ký hiệu phân loại: 615.19 Pharmaceutical chemistry

Thông tin xuất bản: London, UK : IntechOpen, 2020

Mô tả vật lý: 1 electronic resource (164 p.)

Bộ sưu tập: Tài liệu truy cập mở

ID: 224634

The process of drug discovery and development is a complex multistage logistics project spanned over 10-15 years with an average budget exceeding 1 billion USD. Starting with target identification and synthesizing anywhere between 10k to 15k synthetic compounds to potentially obtain the final drug that reaches the market involves a complicated maze with multiple inter- and intra-operative fields. Topics described in this book emphasize the progresses in computational applications, pharmacokinetics advances, and molecular modeling developments. In addition the book also contains special topics describing target deorphaning in Mycobacterium tuberculosis, therapy treatment of some rare diseases, and developments in the pediatric drug discovery process.
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